Drug Interactions and Essential Oils
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Essential Oil & Drug Interactions |
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Essential Oils |
Drugs |
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Angelica |
Warfarin, coumarin |
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Bay Rum |
anticoagulants |
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Bergamot |
Insulin |
|
Birch |
blood thinners |
|
Celery Seed |
ACE inhibitors |
|
Chamomile |
Warfarin, Cyclosporine |
|
Fennel |
Medications containing cytochrome
P450 3A4 |
|
Lavender |
May increase effects of CNS
depressants, anticonvulsants, angicoagulants,
statins, cholesterol-lowering drugs |
|
Manuka |
synergistic effect with bacitracin, cefadroxil, cephradin, and meropenem;
antagonist effect with ofloxacin, enoxacin, and sparfloxacin |
|
Myrrh |
Warfarin, coumarin
derivatives |
|
Orange Bitter |
antidepressants, calcium channel
blockers, destomethorphan, vasoconstrictors |
|
Oregano |
Lithium |
|
Peppermint |
felodipine, simvastatin; absorption of
caffeine; Lexapro |
|
Valerian root |
sedatives, antidepressants |
|
Wintergreen |
Warfarin |
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Drug |
Essential Oils to Avoid |
|
Topical Applications |
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Amittriptiline (elavil an antidepressant) |
German chamomile, Yarrow, Blue tansy |
|
Anticoagulants |
Clove bud, Clove
leaf, Clove stem |
|
Codeine |
German chamomile, Yarrow, Blue tansy |
|
Cyclosporine |
Peppermint |
|
Cyp2B6 (liver
metabolizing enzyme) |
Lemongrass |
|
dermal medications
(patches) |
caution with all essential oils |
|
Fluoxetine (prozac) |
German chamomile, Yarrow, Blue tansy |
|
imipramine |
German chamomile, Yarrow, Blue tansy |
|
Lidocaine |
German chamomile, Yarrow, Blue tansy |
|
Lithium |
Copaiba Balsam |
|
MAORIs or SSRIs |
Clove bud, Clove
leaf, Clove stem |
|
Methadone |
Lemongrass, May chang,
Lemon myrtle, Lemon-scented tea tree |
|
Paroxeline (paxel and other SSRI) |
German chamomile, Yarrow, Blue tansy |
|
Pethidine |
Clove bud, Clove
leaf, Clove stem |
|
Propofol |
Lemongrass, May chang,
Lemon myrtle, Lemon-scented tea tree |
|
taxixofen |
Lemongrass, May chang,
Lemon myrtle, Lemon-scented tea tree |
|
Warfarin |
Birch, Cassia, Cinnamon, Clove,
Fennel, Sweet marjoram, Oregano, Patchouli, Thyme, Wintergreen |
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Inhalation |
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CYP2B6 |
Lemongrass |
|
Warfarin |
Birch, Wintergreen |
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Internal (Not Advised) |
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Aelective serotonin reuptake inhibitors (citalopram, excisertraline,
fluoxetine, paroxetine,sertraline) |
Clove |
|
Antidiabetic drugs (glibenclamide,
tolbutamide, metformin) |
Cassia, Cinnamon, Dill, Sweet fennel,
Lemongrass, Marjoram, Melissa, Oregano |
|
Aspirin |
Birch, Cassia, Cinnamon, Clove,
Fennel, Sweet marjoram, Oregano, Patchouli, Thyme, Wintergreen, Clove bud, Clove leaf, Clove stem |
|
Cyp2B6 |
Melissa |
|
Heparin |
Birch, Cassia, Cinnamon, Clove,
Fennel, Sweet marjoram, Oregano, Patchouli, Thyme, Wintergreen |
|
Indirect
sympathomimetic (ephedrine,
amphetamine) |
Clove bud, Clove
leaf, Clove stem |
|
Monoamine oxidase
inhibiting antidepressants (including isocarboxazid, moclobemide, phenelzine, selegiline, tranylcypromine: |
Clove bud, Clove
leaf, Clove stem |
|
Perhidine |
Clove bud, Clove
leaf, Clove stem |
