Drug Interactions and Essential Oils

Essential Oil & Drug Interactions

Essential Oils

Drugs

Angelica

Warfarin, coumarin

Bay Rum

anticoagulants

Bergamot

Insulin

Birch

blood thinners

Celery Seed

ACE inhibitors

Chamomile

Warfarin, Cyclosporine

Fennel

Medications containing cytochrome P450 3A4

Lavender

May increase effects of CNS depressants, anticonvulsants, angicoagulants, statins, cholesterol-lowering drugs

Manuka

synergistic effect with bacitracin, cefadroxil, cephradin, and meropenem; antagonist effect with ofloxacin, enoxacin, and sparfloxacin

Myrrh

Warfarin, coumarin derivatives

Orange Bitter

antidepressants, calcium channel blockers, destomethorphan, vasoconstrictors

Oregano

Lithium

Peppermint

felodipine, simvastatin; absorption of caffeine; Lexapro

Valerian root

sedatives, antidepressants

Wintergreen

Warfarin

 

 

Drug

Essential Oils to Avoid

Topical Applications

Amittriptiline (elavil an antidepressant)

German chamomile, Yarrow, Blue tansy

Anticoagulants

Clove bud, Clove leaf, Clove stem

Codeine

German chamomile, Yarrow, Blue tansy

Cyclosporine

Peppermint

Cyp2B6 (liver metabolizing enzyme)

Lemongrass

dermal medications (patches)

caution with all essential oils

Fluoxetine (prozac)

German chamomile, Yarrow, Blue tansy

imipramine

German chamomile, Yarrow, Blue tansy

Lidocaine

German chamomile, Yarrow, Blue tansy

Lithium

Copaiba Balsam

MAORIs or SSRIs

Clove bud, Clove leaf, Clove stem

Methadone

Lemongrass, May chang, Lemon myrtle, Lemon-scented tea tree

Paroxeline (paxel and other SSRI)

German chamomile, Yarrow, Blue tansy

Pethidine

Clove bud, Clove leaf, Clove stem

Propofol

Lemongrass, May chang, Lemon myrtle, Lemon-scented tea tree

taxixofen

Lemongrass, May chang, Lemon myrtle, Lemon-scented tea tree

Warfarin

Birch, Cassia, Cinnamon, Clove, Fennel, Sweet marjoram, Oregano, Patchouli, Thyme, Wintergreen

 

 

Inhalation

CYP2B6

Lemongrass

Warfarin

Birch, Wintergreen

 

 

Internal (Not Advised)

Aelective serotonin reuptake inhibitors (citalopram, excisertraline, fluoxetine, paroxetine,sertraline)

Clove

Antidiabetic drugs (glibenclamide, tolbutamide, metformin)

Cassia, Cinnamon, Dill, Sweet fennel, Lemongrass, Marjoram, Melissa, Oregano

Aspirin

Birch, Cassia, Cinnamon, Clove, Fennel, Sweet marjoram, Oregano, Patchouli, Thyme, Wintergreen, Clove bud, Clove leaf, Clove stem

Cyp2B6

Melissa

Heparin

Birch, Cassia, Cinnamon, Clove, Fennel, Sweet marjoram, Oregano, Patchouli, Thyme, Wintergreen

Indirect sympathomimetic (ephedrine, amphetamine)

Clove bud, Clove leaf, Clove stem

Monoamine oxidase inhibiting antidepressants (including isocarboxazid, moclobemide, phenelzine, selegiline, tranylcypromine:

Clove bud, Clove leaf, Clove stem

Perhidine

Clove bud, Clove leaf, Clove stem